1 . (6 pts)  The following statements pertain to the first-day survey and the discussion of it in the following lectures.  Which statements are true?  (multiple True/False = MTF)

 

(A)  The responses indicated that many in our class (e.g., 20% or more) believe/accept concepts for which there is no scientific evidence.

(B)   When surveyed, a large fraction of the U.S. public (e.g., 30% or more) claim to believe concepts for which there is no scientific evidence.

(C)   We suggested that a response indicating uncertainty (in the middle) is evidence that the class is poorly informed about the subject.

(D)  Class responses exhibited a tendency to accept ÒconspiracyÓ theories.  That is, more of the class was willing to accept an idea when couched as a conspiracy than to accept the idea when presented outside a conspiracy context.  This was illustrated with one example.

(E)   We discussed what might be called a Òdecision rule,Ó which consists of the different factors that go into a personÕs acceptance of a statement.  In class, we suggested that the most important factor, the factor that people tend to rely most heavily on, is a personÕs direct knowledge of the evidence.

 

 

 

Scientific Method

 

2). (5 pts) The figure below shows the steps of the scientific method, labeled (i)-(viii).  Which of the following options are true?  You are assumed to know the identity of these steps for this question. In two cases, you are asked to relate the elements of this figure to demonstrations done in class. (MTF)

 

 

 

 

(A)  One of the main themes this figure is used to illustrate is that the scientific method is continual, with no stopping point.

(B)  If data were obtained to evaluate a model, the evaluation would be step (iv)

(C)  For the in-class demonstration using the lamp, the behavior of the lamp in response to the lighter is an example of (v).

(D)  For the in-class demonstration using the ÒWheel of FortuneÓ game, your guesses at letters in the blanks were examples of (i). 

 

3. (4 pts.) Exam Key Code: For 2 points, fill in (AB) on question 3 to indicate your exam code.  Another 2 points is for getting your box number and name bubbled in correctly.


4. (5 pts) For many people, a life ambition is to win the Lotto.  The Lotto is a legal form of gambling in many states in which people attempt to predict (or guess) a set of numbers chosen randomly.  The odds of an exact match are rare, so the reward for winning is high.  The Millionaire Company has just developed a strategy for choosing numbers that it claims have a better-than random chance of winning the Lotto.  A large number of people have used this strategy in recent drawings of the Lotto, and their choices along with the winning numbers have been sent to a statistical consultant to determine if the strategy does indeed perform as advertised, but the statistical consultant has not yet done the analysis.

Which elements of the scientific method are present for use of this method to win the Lotto?  MTF

(A) Goal

(B) Model

(C) Data

(D) Evaluation

(E) Revision

(F) None

 

3. (6 pts) Therapeutic Touch (TT) is a controversial nursing practice that has been taught at UT and elsewhere. Like other nursing practices, TT purports to improve patient healing and overall well-being. People are trained in TT methods by taking classes that provide the basic concepts, and this training enables them to use TT on their own patients. Practitioners steadfastly refuse to subject their methods to rigorous tests that would show whether patients are actually healed faster by TT than without TT, so we don't know if TT has any validity.

5. (5 pts) Astrologists claim to be able to predict your future and give insights to your being, and they have well-defined rules to use in reaching those forecasts, based on your birthday and birth hour.  However, there are no attempts to test the accuracy of those predictions Ð no formal observations, no comparisons of observations to predictions, and no consequent changes in the rules used.

Data is absent in this description.  Why?  MTF

(A)   Evaluation is absent, and there can be no data without evaluation.

(B)   Models are absent.  Without models, you cannot gather data to test the models.

(C)   The problem states that there are no attempts to test the accuracy of the predictions; this statement directly indicates that data is absent.

(D)   The problem states that there are no formal observations, which means that data are not present.

 

 

6. (5 pts)  The State of Texas developed an emergency operations management team used in preparing for the recent hurricane Rita.  This body was established not only to reduce casualties and manage evacuations for hurricanes, but also to contain and minimize damage from other types of potential disasters, including terrorist attacks.  They consulted with personnel who have experience in prior disasters to develop response plans for different types of emergencies.  They also used computer simulations and mock exercises/drills (one on the UT campus) to assess the efficacy of their plans, and the performance in these drills was measured and used to fine-tune their plans.  Hurricane Rita was the first large-scale emergency that this team has faced, and the team has begun gathering Òinformation about the evacuation process and other emergency operationsÓ during Rita to assess performance.

Which of the following points about the scientific method are true, based on the above description? The underlined phrase consists of the goal for this problem. (MTF)

(A)  The response plans constitute models of how actual operations will go.

(B)  The mock exercises/drills represent models of how actual operations will go.

(C)  The only description of data above is in the quoted phrase (Òinformation about...Ó).

(D)  Revision is absent from the above description, because Rita was the first actual emergency, and the problem does not state that any modifications to plans have been made in response to Rita.

 

 

 

7 - 11 (7.5 pts total, 1.5pts each). In the class book, the process of writing a news article was said to resemble the scientific method. Which steps from that example illustrate each of the five elements of the scientific method?

         Use these 5 answers as your list   (A) the current draft of the document

            of choices in 7-11 below:         (B) reactions of you and others to the draft

(C) new drafts

(D) whether the reactions to the draft meets your expectations

(E) writing a stimulating article

 

7.  Goal:                       (A)  (B)  (C)  (D)  (E)  (one answer only)

8.  Model:                    (A)  (B)  (C)  (D)  (E) (one answer only)

9.  Data:                       (A)  (B)  (C)  (D)  (E) (one answer only)

10.  Evaluation:                       (A)  (B)  (C)  (D)  (E) (one answer only)

11. Revision:                (A)  (B)  (C)  (D)  (E) (one answer only)

 

 

12. (5 pts) Which of the following statements apply to our teachings of the scientific method and to violations of the scientific method? (MTF)

A)   Models and evaluation must be closely tied to goals to be useful in the scientific method.

B)    Simple endeavors involving Òtrial and errorÓ illustrate the scientific method

C)    Our understanding of the health effects of tobacco smoke was used to illustrate the final step of the scientific method Ð when we have learned enough that we stop additional testing.

D)   Several social institutions designed to help us (church, government agencies) are lacking one or more elements of the scientific method.

 

 

Models

 

13. (5 pts) Demonstrations.  Lecture used some demonstrations and topics to illustrate the scientific method and others to illustrate models.  Indicate which of the following demos or topics were used to illustrate (some aspects of) models.  If a demo or topic was not used in class, or if it was used to illustrate the scientific method, do not fill it in.  MTF

 

(A) Slogans

(B) Bacteria

(C) ÒSolar systemÓ

(D) Phone book and brochure pictures

(E) Baby oil (in part of one demo)

 

14. (5 pts)  A theme is that all models are false.  Which of the following are consequences of or fixes for this principle?  MTF

 

(A)   Many models used at one time are ultimately replaced by more useful models.

(B)   Because all of our models have flaws, we rarely make progress.

(C)    For any given goal, we often use a patchwork of different models, with one model overcoming the limitations of another. 

(D)    If a model has major limitations, we suggested that this problem should be fixed by choosing a more explicit goal. 

 

 

 

 

 

 

 

15. (5 pts) General points about models.  Which of the following are true?  MTF

 

  1. ACU (accuracy, convenience, uniformity) are characteristics of a model that make it useful.  No one characteristic is necessarily valued above the others.
  2. Although the usefulness of a model depends on the goal, the limitations do not depend on the goal.
  3. A model can be both accurate and convenient, because there is nothing that keeps a model from satisfying several of the 3 ACU criteria.
  4. Our statement that no model exactly matches what it represents is merely a (false) generalization; there are cases in which the model exactly matches its template, as in a Xerox copy or two printings of the same book.

 

 

16. (6 pts) Each of the following options compares two models for a particular goal.  Bubble options in which the first model (in bold) is more accurate than the second model (underlined) for the goal. MTF

(A)   The airburst test instead of Marioposa CSI in tests of condom integrity during sex.

(B)    Yeast instead of mice in tests of whether chemicals inhibit beer cultures (which uses yeast)

(C)    Humans accidentally exposed to dioxin instead of guinea pigs deliberately exposed to dioxin in testing the toxicity of dioxin for humans

(D)   High doses of a pesticide versus low doses of it fed to rats for testing whether traces of the pesticide in food cause cancer.

(E)    Toxicity measures (LD50) versus assays of tumor formation in rats as a measure of a chemicalÕs ability to cause cancer in rats.

 

17. (5 pts) Mark all statements that specifically illustrate the concept that there can be more than one model of any particular object or idea (MTF).

A)   The FBI keeps records on many people.  These records may include fingerprints, DNA profiles, aliases, addresses, and lists of associates and activities.

B)    Our government extrapolates from rodents to estimate a chemicalÕs risk to humans, in part because the number of people exposed to the chemical is too few to rely on just human data.

C)    The ÒremÓ and ÒradÓ as measures of radiation.

D)   Companies use magazine pictures, radio and TV ads and floor models to entice people to buy a product.

 

Condom testing

 

 

18. (5pts) Which of the following were considered goals for condom use and design?

(A) Avoid STD transmission

(B)  Avoid pregnancy

(C)  Maintain sensation

(D) An absence of pores

(E)  Thin, flexible, and durable

 

19. (5pts).  What are limitations of the airburst test as a model of sex to predict whether a condom will stay intact during sex? (pay attention to the goal) MTF

 

A)   The airburst test does not generate the friction and wear that condoms typically experience during sex

B)    The airburst test does not pick up small holes that would allow the passage of a microbe that causes an STD.

C)    The airburst test is not conducted at body temperature and moisture that match sex.

D)   The airburst test cannot be applied to individual condoms that are later sold, because it is a destructive test.

 

20. (3pts) Mechanical tests of condom integrity were considered superior to tests using humans in which property/properties, if any?  MTF

 

(A) Accuracy

(B) Convenience

(C) Uniformity

 

 

 

 

Extrapolating Health Risks

21.  (6pts)  (MTF)

Which of the following illustrate extrapolation across doses?  Some examples were not covered in the book or class, and you need to infer the answer from the option for those.  If the example was covered, then you should only mark it if the statement is true and it illustrates dose extrapolation.

 

A)   One major limitation of the rodent test of carcinogens as model of cancer in humans is that it involves dose extrapolation (a carcinogen is something that increases cancer rates).

B)    New statistical methods allow us to extrapolate from the high exposures smokers receive to low exposures that non-smokers receive.  The harmful effects of second-hand smoke are based primarily on these extrapolations.

C)    As little as 20 years ago, advice to pregnant women was that 1-2 alcoholic drinks per day was acceptable, even though higher levels of consumption were known to be harmful to the fetus.  This advice assumed an extrapolation from high doses.

D)   At a party, Joe has one alcoholic drink and feels good.  He decides to have another drink to feel even better.

 

 

 

22. (6pts) Which points about plants and carcinogens were noted (from the Powerpoint presentation)?  MTF

(A) Many of the plant materials we eat contain substances that test as carcinogens.

(B)  A correlation between diet and cancer has been found in humans.  Higher cancer rates are associated with food plants known to contain carcinogens.

(C)  Roasted coffee tests high in carcinogens.  Yet there is no evidence of higher cancer rates in coffee drinkers.

(D) Synthetic compounds (e.g., pesticides, herbicides, and other man-made chemicals) test positive for cancer at more than twice the level of natural compounds.

(E)  Several herbal remedies have been tested for health effects; the results usually fail to observe a benefit.

(F)  The process of cooking food has been shown conclusively to create harmful substances in some instances.

 

Radiation

 

23. (5pts) The difficulties in estimating harmful effects of excess ionizing radiation include (MTF):

 

A)        We have few people exposed to the low doses that are of greatest interest to us

B)         There is not an accepted way of combining the effects of different types of radiation for measuring its health effects.

C)         The effects of moderate excess doses (e.g., 3 times the annual average) are slight, which makes it difficult to estimate the effects of lower doses

D)        In cases of large exposures, time lags occur between radiation exposure and cancer appearance, so that people exposed may die before they have time to develop a cancer from the radiation

 

24.  (5 points).  Which are true?  MTF

(A)  Compared to adults, the fetal brain is particularly susceptible to radiation and is subject to mental retardation when exposed to elevated levels. 

(B)  The models underlying our understanding of the cancer risk caused by radiation include different types of cancer, different types of radiation, and different doses.

(C)  The types of cancer most commonly studied in conjunction with radiation have been lung, and colon cancer because of their relatively short time-lag between radiation exposure and appearance of the cancer (5 years) compared to the longer lag of leukemia.

(D)  Mice have been used as a model of humans to test which of the abstract models (linear, threshold, ...) best fits the relationship between cancer and radiation because this relationship appears to be insensitive to differences between mice and humans.